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Moxibustion for Chemotherapy-Induced Diarrhea

Moxibustion is an east Asian traditional therapy involving the application of the heat from burning herbs to stimulate specific spots on the skin or acupoints. Moxibustion may be used in combination with acupuncture. This intervention has been examined in people with cancer for its effect on fatigue and diarrhea. 

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Mediterranean Diet

The Mediterranean Diet is a type of eating style limiting process foods, red meat, and sugars and emphasizing fruit, vegetable, grains, beans and nut intake as well as olive oil as a source of healthy fat.

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Herbal Medicine for Chemotherapy-Induced Diarrhea

An herb is a plant or part of a plant that people take for health benefits as dietary supplements or medication. Herbal medicine may also be referred to as phytotherapy or use of botanicals. Herbal medicine interventions include a variety of substances and combinations of substances. Herbal medicine is contraindicated with some chemotherapy agents. 

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Enterade®

Enterade® is a commercially available amino acid-containing electrolyte beverage. In a study of patients undergoing conditioning regimens for autologous stem cell transplantation, the effectiveness of Enterade® was limited by the inability of patients to tolerate rehydration protocols with Enterade® or placebo drinks.

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Cystine and Theanine

Cystine and theanine have been studied for effects on capecitabine-related gastrointestinal symptoms, including diarrhea. Cystine and theanine are amino acid precursors to glutathione which has a role in antioxidative reactions.

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Crofelemer

Crofelemer is a plant-based drug used in adults for the treatment of non-infectious diarrhea associated with antiretroviral treatment for Human Immunodeficiency Virus (HIV) infection. It has been studied as prophylaxis for diarrhea in patients with HER-2 positive breast cancer receiving treatment with trastuzumab, pertuzumab, and taxane regimens.

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Acustimulation for Chemotherapy-Induced Diarrhea

Acustimulation involves electrostimulation of acupressure points (most commonly, the P6 point) by transcutaneous, electrical stimulation. Acustimulation has been studied for chemotherapy-induced diarrhea, chemotherapy-induced nausea and vomiting, and fatigue.

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  • Gregory E. Wilding

  • Jingtao Zhu

  • Fanghong Dong

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