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Matourypour, P., Vanaki, Z., Zare, Z., Mehrzad, V., Dehghan, M., & Ranjbaran, M. (2016). Investigating the effect of therapeutic touch on the intensity of acute chemotherapy-induced vomiting in breast cancer women under chemotherapy. Iranian Journal of Nursing and Midwifery Research, 21, 255–260.
To determine the effect of therapeutic touch on chemotherapy-induced nausea and vomiting (CINV)
Intervention Characteristics/Basic Study Process
Patients were randomly assigned to one of three groups, control receiving no intervention, therapeutic touch, and a placebo intervention. The researcher received training in therapeutic touch and performed these interventions. In the placebo group, the researcher moved her hand around the body to pretend an act of therapeutic touch. CINV was assessed immediately before the intervention and again 24 hours after chemotherapy. Patients were receiving triplet antiemetic prophylaxis.
Sample Characteristics
N = 108
MEAN AGE = 49.7 years (SD = 9.2 years)
FEMALES: 100%
CURRENT TREATMENT: Chemotherapy
KEY DISEASE CHARACTERISTICS: Patients with breast cancer receiving cyclophosphamide and epirubicin
OTHER KEY SAMPLE CHARACTERISTICS: Most had less than a high school education and had no income.
Vomiting intensity was measured on a 0–3 point scale (prior validity measurement was 0.86).
Results
Vomiting intensity was lower in the intervention group compared to the controls (p < 0.0001), but no difference existed between the intervention and placebo groups.
Conclusions
The study results suggested that therapeutic touch may provide a placebo effect to reduce CINV. The efficacy of actual therapeutic touch was not demonstrated compared to placebo.
Limitations
Unintended interventions or applicable interventions not described that would influence results
Measurement validity/reliability questionable
The CINV measurement method was not a commonly used approach, and no information was provided on various response rates.
No information about use of rescue antiemetics was provided, although the methods state that the patients were ordered metoclopramide.
The analysis was unclear, as data was reported in terms of ranking rather than actual outcome measures as collected.
Nursing Implications
The findings did not show the effectiveness of therapeutic touch compared to a placebo intervention to prevent CINV. They do suggest a potential placebo effect for therapeutic touch. This study had several limitations.