Ferreira, E.B., Vasques, C.I., Gadia, R., Chan, R.J., Guerra, E.N., Mezzomo, L.A., . . . Dos Reis, P.E. (2017). Topical interventions to prevent acute radiation dermatitis in head and neck cancer patients: A systematic review. Supportive Care in Cancer, 25, 1001–1011.
STUDY PURPOSE: To evaluate the effects of topical agents in the prevention of radiodermatitis
TYPE OF STUDY: Systematic review
PHASE OF CARE: Active antitumor treatment
Four studies evaluated trolamine. Other interventions were aloe vera, olive oil, Lianbai liquid, sucralfate, Na-SOS, hyaluronic acid, and dexpanthenol. No strong evidence showed differences between topical treatments and control interventions.
The evidence was insufficient to support the use of any of the topical interventions examined.
Insufficient evidence shows the effectiveness of topical agents for the prevention of radiodermatitis.