DNP Projects

A Nursing Educational Intervention to Improve Antiestrogen Adherence and Self-Management of Side Effects

Kaitlyn Fishman

Brittany Rosenthal

Mimi Oupravanh

Emily L. Davenport Alonso

antiestrogen, quality of life, breast cancer survivor, musculoskeletal, patient education
CJON 2022, 26(6), 606-611. DOI: 10.1188/22.CJON.606-611

Antiestrogens prescribed to reduce breast cancer risk or recurrence can have undesirable musculoskeletal side effects that may lead to early discontinuation of therapy. Previous studies have not focused on nurse-led assessment, education, support, and monitoring of antiestrogen-related side effects for patients at high risk for developing breast cancer and breast cancer survivors. This pilot project evaluated the impact of an educational intervention for participants at a community oncology clinic about self- management of antiestrogen-related side effects.

At a Glance

  • Side effects from antiestrogens are a common factor in early discontinuation of therapy. 
  • The literature supports nonpharmacologic methods to manage antiestrogen-related musculoskeletal issues, such as exercise and acupuncture.
  • Nurse-led telehealth patient education about antiestrogen-related musculoskeletal issues may assist in patient management of side effects and improve adherence to therapy.
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