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PI3K Inhibitors and Adverse Events: Optimizing Patient Care for the Treatment of Advanced Breast Cancer

Sarah Donahue
Gretchen Santos Fulgencio
CJON 2020, 24(6), 673-680 DOI: 10.1188/20.CJON.673-680
Background: Excessive activation of the PI3K pathway has been associated with malignant transformation and resistance to treatment in various cancer types. Various PI3K inhibitors have been evaluated in phase 3 clinical trials; however, most have been associated with modest clinical improvement and...
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Oral Mucositis: Examining the Combined Solution of Grape Vinegar and Rose Water Versus Chlorhexidine Mouthwash

Ardashir Afrasiabifar
Narges Jafari Dehkordi
Asadolah Mosavi
Mohammad Amin Nazer Mozaffari
Zeinab Ali Beigi Bani
CJON 2020, 24(6), E71-E78 DOI: 10.1188/20.CJON.E71-E78
Background: Studies have reported contradictory findings regarding the efficacy of chemical mouthwashes for chemotherapy-induced oral mucositis. Objectives: This study sought to compare the effect of the combined solution of grape vinegar and rose water versus chlorhexidine mouthwash on...
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NCPD Article
Supportive Care

Shared Decision-Making Competency: Provider-Specific Factors in Hematology-Oncology Clinical Practice

Joseph D. Tariman
Alexandria Tarvainis
Kashica J. Webber-Ritchey
Shannon D. Simonovich
CJON 2020, 24(4), 346-351 DOI: 10.1188/20.CJON.346-351
A computerized database search was performed using PubMed ® , CINAHL ® , and EBSCOhost to identify provider-specific factors associated with shared decision-making (SDM) competency among direct patient care providers in hematology-oncology practice. Personal factors included being female or older...
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Article

Appendiceal Mucinous Neoplasm: Nurse Education About a Rare and Complex Disease

Alaine M. Kamm
Kiran K. Turaga
CJON 2020, 24(4), 409-414 DOI: 10.1188/20.CJON.409-414
Background: Appendiceal mucinous neoplasms (AMNs) are a rare and complex spectrum of disease involving a mucinous tumor within the appendix, which can range from benign to malignant. If not limited to the appendix, the mucinous tumor can spread diffusely throughout the peritoneum. Objectives:...
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Article

Acalabrutinib: Managing Adverse Events and Improving Adherence in Patients With Mantle Cell Lymphoma

Maria Badillo
Diana Nava
Maria Dela Rosa
Wendy Chen
Maria Guerrero
Michael Wang
CJON 2020, 24(4), 392-398 DOI: 10.1188/20.CJON.392-398
Background: Acalabrutinib is a selective Bruton tyrosine kinase inhibitor approved for patients with relapsed or refractory mantle cell lymphoma, an aggressive B-cell malignancy. Treatment-related adverse events (AEs) can have a negative effect on treatment adherence. Objectives: This article aims...
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