Cancer intervention strategies have been increasingly focused on developing therapies that are personalized and tailored to each individual's unique genetic profile. Evolving understanding of the metabolism and pharmacogenomics of tamoxifen, an early example of targeted therapy for women with...

A 57-year-old woman named C. B. began experiencing abdominal pain and bloating. She presented to her primary physician with these symptoms, and her physician palpated an adenexal mass on pelvic examination. That prompted a computed tomography (CT) scan of the abdomen and pelvis, which demonstrated...

Purpose/Objectives: To clarify the concept of adherence to daily oral chemotherapy in children with acute lymphoblastic leukemia (ALL), to examine its implications for clinical practice, and to provide a foundation for further research and knowledge development. Data Sources: Published literature...

Purpose/Objectives: To assess the validity of neuropathy and neuropathic pain-measurement approaches. Design: Cross-sectional measurement study. Setting: Two comprehensive cancer centers in the northeastern United States. Sample: 117 patients with cancer in an outpatient setting. Methods:...