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Advanced Practice

Dronabinol Therapy: Central Nervous System Adverse Events in Adults With Primary Brain Tumors

Deborah “Hutch” Allen
CJON 2019, 23(1), 23-26 DOI: 10.1188/19.CJON.23-26
Dronabinol is an effective adjunct to antiemetic regimens during cancer treatment in several populations of patients with cancer. However, it has been used little in central nervous system (CNS) cancers because of concerns regarding potential CNS adverse events. This secondary analysis explored CNS...
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Systematic Review of Nonpharmacologic Approaches for the Management of Gastrointestinal Symptoms

Catherine Cherwin
Lynn Nakad
Alaa Albashayreh
ONF 2019, 46(1), E1-E21 DOI: 10.1188/19.ONF.E1-E21
Problem Identification: To summarize and critique the literature for nonpharmacologic complementary approaches to manage gastrointestinal (GI) symptoms attributed to chemotherapy. Literature Search: A literature search was conducted using CINAHL®, MEDLINE®, and PsycINFO® from database inception...
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Antiemetic Guidelines: Using Education to Improve Adherence and Reduce Incidence of CINV in Patients Receiving Highly Emetogenic Chemotherapy

Corrine Mellin
Mallory Lexa
Ashley Leak Bryant
Susie Mason
Deborah K. Mayer
CJON 2018, 22(3), 297-303 DOI: 10.1188/18.CJON.297-303
Background: With the development of increasingly effective antiemetic regimens, guideline adherence can prevent 70%–80% of chemotherapy-induced nausea and vomiting (CINV) in patients with cancer. Objectives: This quality improvement project aims to increase rates of adherence to national guidelines...
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Cisplatin-Based Therapy and CINV: Optimal Antiemetics During Germ Cell Testicular Cancer Treatment

Meghan Mastrangelo
CJON 2018, 22(2), E31-E36 DOI: 10.1188/18.CJON.E31-E36
Background: Cisplatin-based chemotherapy regimens are the backbone of chemotherapy for germ cell testicular cancer. Cisplatin is administered for five days, causing an overlap of acute and delayed chemotherapy-induced nausea and vomiting (CINV). Although CINV is widely researched, studies involving...
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Fixed Combination Antiemetic: A Literature Review on Prevention of Chemotherapy-Induced Nausea and Vomiting Using Netupitant/Palonosetron

Rebecca A. Clark-Snow
Cheryl Vidall
Sussanne Börjeson
Patrick Jahn
CJON 2018, 22(2), E52-E63 DOI: 10.1188/18.CJON.E52-E63
Background: Prevention of chemotherapy-induced nausea and vomiting (CINV) can be improved with guideline-consistent use of antiemetics. However, adherence to antiemetic guidelines remains often insufficient. Therefore, new strategies that improve adherence are needed. Objectives: To review the...
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