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Immunotherapy: Exploring the State of the Science

Pamela K. Ginex
Kelly Brassil
Beth Ely
CJON 2017, 21(2), 9-12 DOI: 10.1188/17.CJON.S2.9-12
Immunotherapy research provides opportunities for nurse scientists and researchers to be at the forefront of the changing landscape of cancer treatment. As these therapies continue to develop, current initiatives will seek to support nurses in clinical practice who must provide safe, evidence-based...
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Checkpoint Inhibitors: Common Immune-Related Adverse Events and Their Management

RuthAnn Gordon
Mary Kate Kasler
Kristen Stasi
Yelena Shames
Mimma Errante
Kathryn Ciccolini
Anna Skripnik Lucas
Pam Raasch
Erica Fischer-Cartlidge
CJON 2017, 21(2), 45-52 DOI: 10.1188/17.CJON.S2.45-52
Background: Immunotherapy, specifically the use of checkpoint inhibitors, offers patients with cancer an alternative to chemotherapy, targeting different pathways to destroy cancer cells. The side effects of immunotherapies, as well as their impact on normal tissue, need to be assessed and managed...
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Article

CAR T-Cell Therapy: Pediatric Patients With Relapsed and Refractory Acute Lymphoblastic Leukemia

Colleen Callahan
Diane Baniewicz
Beth Ely
CJON 2017, 21(2), 22-28 DOI: 10.1188/17.CJON.S2.22-28
Background: Immunotherapy provides a promising treatment option for children and adolescents with refractory or relapsed acute lymphoblastic leukemia (ALL). Objectives: This article presents a hospital’s experience with providing chimeric antigen receptor (CAR) T-cell therapy, followed by a...
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Cancer Immunotherapy: An Evidence-Based Overview and Implications for Practice

Virginia Bayer
Beau Amaya
Diane Baniewicz
Colleen Callahan
Lisa Marsh
Asia S. McCoy
CJON 2017, 21(2), 13-21 DOI: 10.1188/17.CJON.S2.13-21
Background: Significant research progress has been made in immunotherapies since the mid-1990s, and this rapid evolution necessitates evidence-based education on immunotherapies, their pathophysiology, and their toxicities to provide safe, effective care. Objectives: The aim of this article is to...
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Article

Immunotherapy Administration: Oncology Nursing Society Recommendations

Kathleen Wiley
Kristine B. LeFebvre
Lisa Wall
Abigail Baldwin-Medsker
Kim Nguyen
Lisa Marsh
Diane Baniewicz
CJON 2017, 21(2), 5-7 DOI: 10.1188/17.CJON.S2.5-7
As the use of immunotherapeutic agents increases in single-agent and multimodality treatment regimens, oncology nurses face the challenge of administering and caring for patients receiving new and unique agents. Oncology Nursing Society clinical staff and clinical nurses collaborated to produce a...
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