Background: In the management of lung cancer, molecular profiling of the tumor is pivotal to defining a personalized treatment plan and is recommended for each patient. Objectives: The purpose of this article is to provide an update on genomic testing in lung cancer and the associated targeted...

Tumor genomic testing is used primarily to facilitate the selection of the best possible treatment for a malignancy based on the genomic characteristics of the tumor. Germline genomic testing has implications for care and recommendations for cancer prevention and early detection for the patient and...

Background: Elucidation of key biomarkers, as indicators and drivers of the pathologic processes in cutaneous melanoma (CM), has led to the development of effective targeted therapies. Objectives: This article provides an overview of key concepts in advanced CM, particularly the essential role of...

Precision medicine has revolutionized multiple facets of care across the cancer trajectory, from prevention through treatment. Sometimes referred to as personalized medicine, precision medicine uses information contained in an individual’s genes, as well as biomarkers and genetic alterations...