1. Home
  2. Category
  3. Treatment Types

Clinical Trials

CNE Article

CAR T-Cell Therapy: Update on the State of the Science

Misty Lamprecht
Colleen Dansereau
CJON 2019, 23(2), 6-12 DOI: 10.1188/19.CJON.S1.6-12
Background: Chimeric antigen receptor (CAR) T-cell therapy leverages the power of the patient’s own immune system by serving as a bridge to connect genetically modified T cells to the surface antigens of tumor cells based on targeted ligands. Clinical trials have demonstrated compelling overall...
5
Average: 5 (1 vote)
Read this Article
Communities

Cancer Clinical Trials: Improving Awareness and Access for Minority and Medically Underserved Communities

Melissa Beauchemin
Grace Hillyer
Diane St. Germain
CJON 2019, 23(2), 220-223 DOI: 10.1188/19.CJON.220-223
Cancer clinical trials offer patients an opportunity to receive new and innovative treatment, as well as contribute to the future of cancer care. Enrollment onto clinical trials also may lead to better care and outcomes; however, few adult patients with cancer and even fewer ethnic and racial...
0
No votes yet
Read this Article
Online Exclusive Article

Administration of Subcutaneous Monoclonal Antibodies in Patients With Cancer

Anne Rodrigues Ferreira
Eliete Farias Azevedo
ONF 2019, 46(1), E38-E47 DOI: 10.1188/19.ONF.E38-E47
Problem Identification: Subcutaneous (SC) formulations for monoclonal antibodies (mAbs) must be evaluated for efficacy and safety in comparison with preexisting IV formulations to identify potential benefits and risks. Literature Search: This is a systematic review of clinical trials. MEDLINE®/...
0
No votes yet
Read this Article
Online Exclusive Article

Clinical Trials Informed Consent: An Educational Intervention to Improve Nurses’ Knowledge and Communications Skills

Eileen M. Regan
CJON 2018, 22(6), E152-E158 DOI: 10.1188/18.CJON.E152-E158
Background: Teach-back is an evidence-based tool recommended for use during informed consent (IC) discussions. The nurses’ role in the IC process is important, particularly for patient education and advocacy. Objectives: The aim was to initiate and evaluate an educational program for nurses to...
0
No votes yet
Read this Article
Online Exclusive Article

Well-Being of Child and Family Participants in Phase 1 Pediatric Oncology Clinical Trials

Stacey Crane
Joan E. Haase
Susan E. Hickman
ONF 2018, 45(5), E67-E97 DOI: 10.1188/18.ONF.E67-E97
Problem Identification: Pediatric oncology phase 1 clinical trials (P1Ts) are essential to developing new anticancer therapies; however, they raise complex ethical concerns about balancing the need for this research with the well-being of participating children. The purpose of this integrative...
0
No votes yet
Read this Article

Related e-Books

View More

Questions, Concerns or Requests

We're just a click away for assistance.