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Article

PI3K Inhibitors and Adverse Events: Optimizing Patient Care for the Treatment of Advanced Breast Cancer

Sarah Donahue
Gretchen Santos Fulgencio
CJON 2020, 24(6), 673-680 DOI: 10.1188/20.CJON.673-680
Background: Excessive activation of the PI3K pathway has been associated with malignant transformation and resistance to treatment in various cancer types. Various PI3K inhibitors have been evaluated in phase 3 clinical trials; however, most have been associated with modest clinical improvement and...
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Article

Breast Cancer Screening Knowledge, Attitudes, and Practices Among Korean American Women

Youngshook Han
Roma D. Williams
Renee A. Harrison
ONF 2000, 27(10), 1585-1591 DOI:
Purpose/Objectives: To describe the knowledge and beliefs about breast cancer and breast cancer screen­ng and practices of clinical breast examination (CBE) and mammography of Korean American women. Design: Cross-sectional survey. Setting: Two Korean churches in a mid-sized Southeastern U.S. city...
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Quality of Life, Survivorship, and Psychosocial Adjustment of Young Women With Breast Cancer After Breast-Conserving Surgery and Radiation Therapy

Karen Hassey Dow
Patricia Lafferty
ONF 2000, 27(10), 1555-1564 DOI:
Purpose/Objectives: To examine changes In quality of life (QOL), psychosocial adjustment, and survivorship issues over time of women younger than 45 years who underwent breast-conserving surgery and radiation therapy (RT) for breast cancer. Design: Repeated measures, longitudinal design. Methods:...
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Article

Prophylactic Mastectomy and Genetic Testing: An Update

Shauna L. Houshmand
Craig T. Campbell
Sheri E. Briggs
Andrew W.J. McFadden
Toher AI-Tweigeri
ONF 2000, 27(10), 1537-1547 DOI:
Purpose/Objectives: To examine and discuss the pos­sible benefits and difficulties with recommending pro­phylactic mastectomy to BRCA1- and BRCA2-positive women. Data Sources: Published research articles, profes­sional review articles, textbooks. Data Synthesis: Women with BRCA1 and BRCA2 mu­...
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Article

Relations of Mindfulness and Illness Acceptance With Psychosocial Functioning in Patients With Metastatic Breast Cancer and Caregivers

Kelly Chinh
Ekin Secinti
Shelley A. Johns
Adam T. Hirsh
Kathy D. Miller
Bryan Schneider
Anna Maria Storniolo
Lida Mina
Erin V. Newton
Victoria L. Champion
Catherine E. Mosher
ONF 2020, 47(6), 739-752 DOI: 10.1188/20.ONF.739-752
Objectives: To examine relationships in mindfulness and illness acceptance and psychosocial functioning in patients with metastatic breast cancer and their family caregivers. Sample & Setting: 33 dyads from an academic cancer center in the United States. Methods & Variables: Participants...
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